Stadium: Jack Spinks Stadium Round: 1
Home Manager: Fred McNair Away Manager: Eric Dooley
| NCAAF | 2022/10/15 23:00 | Alcorn State v Southern | W | 17-21 |
| NCAAF | 2021/10/30 23:00 | Alcorn State v Southern | W | 35-38 |
| NCAAF | 2019/12/07 21:00 | Southern v Alcorn State | L | 24-39 |
| NCAAF | 2019/10/26 19:00 | Southern v Alcorn State | L | 13-27 |
| NCAAF | 2018/12/01 21:30 | Southern v Alcorn State | L | 28-37 |
| NCAAF | 2018/09/29 23:00 | Alcorn State v Southern | L | 20-3 |
| NCAAF | 2017/09/23 23:00 | Alcorn State v Southern | L | 48-31 |