Stadium: Jack Spinks Stadium Round: 1
Home Manager: Fred McNair Away Manager: Eric Dooley
| NCAAF | 2022/10/15 23:00 | Alcorn State v Southern | W | 17-21 |
| NCAAF | 2021/10/30 23:00 | Alcorn State v Southern | W | 35-38 |
| NCAAF | 2019/12/07 21:00 | Southern v Alcorn State | L | 24-39 |
| NCAAF | 2019/10/26 19:00 | Southern v Alcorn State | L | 13-27 |
| NCAAF | 2018/12/01 21:30 | Southern v Alcorn State | L | 28-37 |
| NCAAF | 2018/09/29 23:00 | Alcorn State v Southern | L | 20-3 |
| NCAAF | 2017/09/23 23:00 | Alcorn State v Southern | L | 48-31 |
| NCAAF | 2023/10/28 21:00 | Texas Southern v Southern | W | 17-23 |
| NCAAF | 2023/10/21 20:00 | Southern v Bethune-Cookman | W | 28-18 |
| NCAAF | 2023/10/14 21:00 | Southern v Lincoln Oaklanders | W | 45-18 |
| NCAAF | 2023/10/07 23:00 | Florida A&M v Southern | L | 26-19 |
| NCAAF | 2023/09/30 21:00 | Southern v Arkansas-Pine Bluff | W | 27-0 |
| NCAAF | 2023/09/16 23:00 | Alabama A&M v Southern | W | 10-20 |
| NCAAF | 2023/09/09 23:00 | Jackson State v Southern | L | 27-14 |
| NCAAF | 2023/09/02 22:00 | Southern v Alabama State | L | 10-14 |
| NCAAF | 2023/10/28 19:00 | Mississippi Valley v Alcorn State | W | 3-24 |
| NCAAF | 2023/10/21 19:00 | Alcorn State v Arkansas-Pine Bluff | W | 31-7 |
| NCAAF | 2023/10/07 19:30 | Grambling State v Alcorn State | W | 24-25 |
| NCAAF | 2023/09/30 22:00 | Alcorn State v Alabama State | W | 23-20 |
| NCAAF | 2023/09/23 23:00 | Prairie View A&M v Alcorn State | L | 23-20 |
| NCAAF | 2023/09/16 23:00 | McNeese State v Alcorn State | W | 3-17 |
| NCAAF | 2023/09/09 23:00 | Alcorn State v Stephen F. Austin | L | 10-38 |
| NCAAF | 2023/09/02 23:00 | Alcorn State v Southern Miss | L | 14-40 |