[5] Stefanos Tsitsipas 5-7,6-3,7-6,6-1 Isner, John [34] 2021-06-04 19:00
Stadium: Court Philippe Chatrier Round: 25 Ground: Clay
Face à face
| ATP - Acapulco | 2021/03/18 04:00 | Stefanos Tsitsipas v Isner, John | 6-3,6-2 |
| New York, USA | 2020/08/25 21:30 | Isner, John v Stefanos Tsitsipas | 6-7,6-7 |
| Pékin, Chine | 2019/10/04 08:50 | Isner, John v Stefanos Tsitsipas | 6-7,3-6 |
| Wimbledon, London, Great Britain | 2018/07/09 13:40 | Isner, John v Stefanos Tsitsipas | 6-4,7-6,7-6 |
| Shanghai, Chine | 2017/10/11 12:20 | Stefanos Tsitsipas v Isner, John | 6-7,6-7 |