[5] Stefanos Tsitsipas 5-7,6-3,7-6,6-1 Isner, John [34] 2021-06-04 19:00
Stadium: Court Philippe Chatrier Round: 25 Ground: Clay
Face à face
| ATP - Acapulco | 2021/03/18 04:00 | Stefanos Tsitsipas v Isner, John | 6-3,6-2 |
| New York, USA | 2020/08/25 21:30 | Isner, John v Stefanos Tsitsipas | 6-7,6-7 |
| Pékin, Chine | 2019/10/04 08:50 | Isner, John v Stefanos Tsitsipas | 6-7,3-6 |
| Wimbledon, London, Great Britain | 2018/07/09 13:40 | Isner, John v Stefanos Tsitsipas | 6-4,7-6,7-6 |
| Shanghai, Chine | 2017/10/11 12:20 | Stefanos Tsitsipas v Isner, John | 6-7,6-7 |
Home History
| French Open, Paris, France | 2021/06/02 13:50 | Stefanos Tsitsipas v Pedro Martinez | 6-3,6-4,6-3 |
| French Open, Paris, France | 2021/05/30 18:30 | Stefanos Tsitsipas v Chardy, Jérémy | 7-6,6-3,6-1 |
| Lyon, France | 2021/05/23 12:00 | Cameron Norrie v Stefanos Tsitsipas | 3-6,3-6 |
| Lyon, France | 2021/05/22 12:00 | Lorenzo Musetti v Stefanos Tsitsipas | 6-4,3-6,0-6 |
| Lyon, France | 2021/05/21 10:20 | Yoshihito Nishioka v Stefanos Tsitsipas | 3-6,4-6 |
| Lyon, France | 2021/05/20 13:00 | Tommy Paul v Stefanos Tsitsipas | 1-6,4-6 |
| ATP - Rome | 2021/05/14 12:25 | Novak Djokovic v Stefanos Tsitsipas | 4-6,7-5,7-5 |
| ATP - Rome | 2021/05/13 10:00 | Matteo Berrettini v Stefanos Tsitsipas | 6-7,2-6 |
Away History
| French Open, Paris, France | 2021/06/02 12:35 | Filip Krajinovic v Isner, John | 6-7,1-6,6-7 |
| French Open, Paris, France | 2021/05/31 09:00 | Querrey, Sam v Isner, John | 6-7,3-6,4-6 |
| ATP - Madrid | 2021/05/07 11:00 | Dominic Thiem v Isner, John | 3-6,6-3,6-4 |
| ATP - Madrid | 2021/05/06 13:20 | Isner, John v Andrey Rublev | 7-6,3-6,7-6 |
| ATP - Madrid | 2021/05/05 16:00 | Bautista-Agut, Roberto v Isner, John | 4-6,7-6,6-7 |
| ATP - Madrid | 2021/05/03 09:00 | Isner, John v Miomir Kecmanovic | 6-4,7-6 |
| ATP - Miami | 2021/03/30 15:00 | Isner, John v Bautista-Agut, Roberto | 3-6,6-4,6-7 |
| ATP - Miami | 2021/03/28 15:00 | Felix Auger Aliassime v Isner, John | 6-7,6-7 |