| Challenger Knoxville | 11/07 00:05 | 25 | [140] Smyczek, Tim v Smith, John-Patrick [202] | 3-6,6-3,6-2 | |
| Challenger Charlottesville | 11/01 19:30 | 26 | [120] Smyczek, Tim v Thai-Son Kwiatkowski [346] | 2-6,7-5,2-6 | |
| Challenger Charlottesville | 10/31 16:50 | 25 | [120] Smyczek, Tim v Blaz Rola [230] | 6-4,7-5 | |
| Shanghai, Chine | 10/06 04:00 | 45 | [111] Smyczek, Tim v Taro Daniel [72] | 7-6,4-6,4-6 | |
| ATP Tokyo | 09/29 02:00 | 64 | [273] Yosuke Watanuki v Smyczek, Tim [109] | 6-4,6-2 | |
| Chengdu, Chine | 09/24 05:00 | 25 | [50] Joao Sousa v Smyczek, Tim [109] | 7-6,6-7,6-3 | |
| ATP Shenzhen | 09/22 07:20 | 64 | Smyczek, Tim v Fajing Sun | Cancelled | |
| US Open, New York, USA | 08/28 15:00 | 23 | [103] Smyczek, Tim v Jan-Lennard Struff [58] | 6-7,4-6,3-6 | |
| ATP Cincinnati Qual | 08/12 14:00 | 46 | [102] Smyczek, Tim v Michael Mmoh [135] | 1-6,6-2,2-6 | |
| ATP Cincinnati Qual | 08/11 14:30 | 45 | [53] John Millman v Smyczek, Tim [102] | Retired | |
| ATP Toronto Qual | 08/04 15:00 | 45 | [128] Mahut, Nicolas v Smyczek, Tim [101] | 7-6,3-6,7-5 | |
| Washington, USA | 08/01 17:25 | 25 | [101] Smyczek, Tim v Zverev, Mischa [42] | 2-6,6-7 | |
| Washington, USA | 07/30 19:35 | 24 | [101] Smyczek, Tim v Ricardas Berankis [94] | 7-6,6-2 | |
| Atlanta, USA | 07/24 20:50 | 25 | [102] Smyczek, Tim v Zverev, Mischa [45] | 3-6,7-6,3-6 | |
| Newport, USA | 07/21 18:00 | 28 | [123] Smyczek, Tim v Ramkumar Ramanathan [161] | 4-6,5-7 | |
| Newport, USA | 07/19 16:30 | 27 | [131] Jason Jung v Smyczek, Tim [123] | 1-6,7-5,4-6 | |
| Newport, USA | 07/18 16:25 | 26 | [123] Smyczek, Tim v Ebden, Matthew [43] | 6-3,6-3 | |
| Newport, USA | 07/16 18:05 | 25 | [133] Fratangelo, Bjorn v Smyczek, Tim [123] | 3-6,6-2,4-6 | |
| Winnetka, USA | 07/10 00:00 | 25 | [113] Smyczek, Tim v Tommy Paul [195] | 6-1,6-7,4-6 | |
| London, Great Britain | 06/19 14:20 | 25 | [121] Smyczek, Tim v Chardy, Jérémy [61] | 2-6,4-6 | |
| ATP Queens Qual | 06/17 10:30 | 164 | [150] Thanasi Kokkinakis v Smyczek, Tim [125] | 6-2,4-6,3-6 | |
| ATP Queens Qual | 06/16 10:00 | 64 | [125] Smyczek, Tim v Mikhail Kukushkin [86] | 6-4,3-6,7-6 | |
| s-Hertogenbosch, Netherlands | 06/12 10:35 | 25 | [69] Ebden, Matthew v Smyczek, Tim [125] | 6-2,6-3 | |
| s-Hertogenbosch, Netherlands, Qualifying | 06/10 13:30 | 164 | [118] Smyczek, Tim v Bernard Tomic [206] | 4-6,2-6 | |
| s-Hertogenbosch, Netherlands, Qualifying | 06/09 13:50 | 64 | [118] Smyczek, Tim v Zapata Miralles, Bernabe [253] | 7-6,6-3 | |
| French Open Qual | 05/21 13:25 | 44 | [118] Smyczek, Tim v Jaume Munar [155] | 3-6,5-7 | |
| ATP - Estoril | 05/01 12:55 | 25 | [123] Smyczek, Tim v Nicolas Kicker [93] | 2-6,2-6 | |
| ATP Estoril Qual | 04/30 11:00 | 45 | [123] Smyczek, Tim v Gil, Fred [445] | 6-4,6-2 | |
| ATP Estoril Qual | 04/28 11:00 | 44 | [123] Smyczek, Tim v Cabral, Francisco [313] | 6-2,6-1 | |
| ATP Budapest Qual | 04/21 08:30 | 26 | [137] Zopp, Jurgen v Smyczek, Tim [123] | 1-6,6-4,6-4 |