| NCAAF | 11/12 00:00 | 1 | Carnegie Mellon Tartans v Case Western Reserve Spartans | L | 31-21 | |
| NCAAF | 11/04 18:00 | 1 |
Case Western Reserve Spartans
v
Allegheny Gators
|
W | 42-14 | |
| NCAAF | 10/28 22:05 | 1 | Washington And Jefferson Presidents v Case Western Reserve Spartans | L | 38-33 | |
| NCAAF | 10/21 18:00 | 1 | Case Western Reserve Spartans v Waynesburg Yellow Jackets | W | 35-0 | |
| NCAAF | 10/14 18:00 | 1 | Case Western Reserve Spartans v Westminster Titans | W | 31-6 | |
| NCAAF | 10/07 17:00 | 1 | Saint Vincent v Case Western Reserve Spartans | W | 0-19 | |
| NCAAF | 09/30 18:30 | 1 | Bethany Bison v Case Western Reserve Spartans | W | 12-34 | |
| NCAAF | 09/23 23:00 | 1 | Case Western Reserve Spartans v Geneva Golden Tornadoes | W | 42-7 | |
| NCAAF | 09/16 23:00 | 1 | Case Western Reserve Spartans v Grove City Wolverines | L | 24-27 | |
| NCAAF | 09/02 23:00 | 1 | Thiel Tomcats v Case Western Reserve Spartans | W | 0-14 | |
| NCAAF | 11/12 19:00 | 1 | Case Western Reserve Spartans v Carnegie Mellon Tartans | L | 7-20 | |
| NCAAF | 11/05 17:00 | 1 | Westminster Titans v Case Western Reserve Spartans | L | 14-13 | |
| NCAAF | 10/29 17:00 | 1 |
Allegheny Gators
v
Case Western Reserve Spartans
|
W | 7-54 | |
| NCAAF | 10/22 18:00 | 1 | Case Western Reserve Spartans v Bethany Bison | W | 45-7 | |
| NCAAF | 10/08 17:00 | 1 | Case Western Reserve Spartans v Saint Vincent | W | 45-21 | |
| NCAAF | 10/01 18:00 | 1 | Grove City Wolverines v Case Western Reserve Spartans | L | 14-13 | |
| NCAAF | 09/24 23:00 | 1 | Geneva Golden Tornadoes v Case Western Reserve Spartans | W | 7-34 | |
| NCAAF | 09/17 23:00 | 1 | Case Western Reserve Spartans v Washington And Jefferson Presidents | W | 14-10 | |
| NCAAF | 09/10 17:00 | 1 | Waynesburg Yellow Jackets v Case Western Reserve Spartans | W | 31-45 | |
| NCAAF | 09/03 16:00 | 1 | Case Western Reserve Spartans v Johns Hopkins Blue Jays | L | 14-54 | |
| NCAAF | 11/13 18:00 | 1 | Carnegie Mellon Tartans v Case Western Reserve Spartans | L | 24-6 | |
| NCAAF | 11/06 17:00 | 1 | Case Western Reserve Spartans v Grove City Wolverines | W | 35-21 | |
| NCAAF | 10/30 17:00 | 1 | Thiel Tomcats v Case Western Reserve Spartans | W | 12-30 | |
| NCAAF | 10/23 17:30 | 1 | Case Western Reserve Spartans v Geneva Golden Tornadoes | W | 42-38 | |
| NCAAF | 10/16 18:00 | 1 | Case Western Reserve Spartans v Bethany Bison | W | 53-0 | |
| NCAAF | 10/02 17:00 | 1 | Saint Vincent v Case Western Reserve Spartans | L | 42-40 | |
| NCAAF | 09/25 23:00 | 1 | Case Western Reserve Spartans v Washington And Jefferson Presidents | L | 14-37 | |
| NCAAF | 09/18 23:00 | 1 | Case Western Reserve Spartans v Westminster Titans | L | 12-34 | |
| NCAAF | 09/11 17:00 | 1 | Waynesburg Yellow Jackets v Case Western Reserve Spartans | W | 33-66 | |
| NCAAF | 09/04 23:00 | 1 | Rochester Yellowjackets v Case Western Reserve Spartans | W | 20-27 |