Stadium: O'Kelly-Riddick Stadium Round: 1
| NCAAF | 2022/09/10 22:00 | N.C. Central v Winston-Salem State | W | 41-0 |
| NCAAF | 2021/09/18 22:00 | N.C. Central v Winston-Salem State | W | 20-13 |
| Collegiate Bowl Games | 2022/12/17 17:00 | Jackson State v N.C. Central | W | 34-41 |
| NCAAF | 2022/11/19 19:30 | N.C. Central v Tennessee Tech | W | 22-20 |
| NCAAF | 2022/11/12 19:00 | N.C. Central v Norfolk State | W | 48-14 |
| NCAAF | 2022/11/05 18:00 | Howard v N.C. Central | W | 21-50 |
| NCAAF | 2022/10/29 18:00 | N.C. Central v Delaware State | W | 28-21 |
| NCAAF | 2022/10/22 17:30 | N.C. Central v South Carolina State | L | 24-26 |
| NCAAF | 2022/10/13 23:30 | Morgan State v N.C. Central | W | 20-59 |
| NCAAF | 2022/10/01 16:00 | Campbell v N.C. Central | L | 48-18 |
| NCAAF | 2022/11/05 20:00 | Winston-Salem State v Fayetteville State Broncos | L | 6-14 |
| NCAAF | 2022/10/29 17:00 | Winston-Salem State v Johnson C. Smith | W | 28-7 |
| NCAAF | 2022/10/22 17:00 | St Augustines Falcons v Winston-Salem State | W | 14-41 |
| NCAAF | 2022/10/15 17:30 | Winston-Salem State v Shaw Bears | W | 17-10 |
| NCAAF | 2022/10/08 17:00 | Livingstone v Winston-Salem State | L | 20-17 |
| NCAAF | 2022/09/24 22:00 | Chowan University v Winston-Salem State | L | 21-7 |
| NCAAF | 2022/09/17 16:00 | Elizabeth City State Vikings v Winston-Salem State | L | 20-17 |
| NCAAF | 2022/09/10 22:00 | N.C. Central v Winston-Salem State | L | 41-0 |