Face à face
| Chili - Primera B | 2017/11/05 20:00 | Cobreloa v La Serena | W | 4-0 |
| Chili - Primera B | 2017/04/14 21:00 | La Serena v Cobreloa | W | 1-2 |
| Chili - Primera B | 2016/11/05 22:00 | Cobreloa v La Serena | L | 0-2 |
| Chili - Coupe du Chili | 2016/09/28 22:00 | La Serena v Cobreloa | D | 0-0 |
| Chili - Coupe du Chili | 2016/09/15 23:00 | Cobreloa v La Serena | W | 3-0 |
| Chili - Primera B | 2016/04/09 21:00 | Cobreloa v La Serena | L | 2-3 |
| Chili - Primera B | 2015/11/07 20:00 | La Serena v Cobreloa | D | 0-0 |
Home History
| Chili - Primera B | 2018/03/24 21:00 | Puerto Montt v Cobreloa | D | 0-0 |
| Chili - Primera B | 2018/03/18 21:00 | Cobreloa v Deportes Valdivia | W | 2-0 |
| Chili - Primera B | 2018/03/03 23:00 | Coquimbo Unido v Cobreloa | L | 2-0 |
| Chili - Primera B | 2018/02/25 21:00 | San Marcos de Arica v Cobreloa | L | 2-1 |
| Chili - Primera B | 2018/02/18 21:00 | Cobreloa v Rangers de Talca | W | 3-1 |
| Chili - Primera B | 2018/02/11 21:00 | Deportes Copiapo v Cobreloa | D | 0-0 |
| Chili - Primera B | 2018/02/04 21:00 | Cobreloa v Cobresal | W | 1-0 |
| Chili - Primera B | 2017/11/13 23:00 | Union La Calera v Cobreloa | L | 3-0 |
Away History
| Chili - Primera B | 2018/03/25 19:30 | La Serena v Magallanes | D | 0-0 |
| Chili - Primera B | 2018/03/09 21:30 | Melipilla v La Serena | L | 2-0 |
| Chili - Primera B | 2018/03/03 20:00 | Puerto Montt v La Serena | W | 1-2 |
| Chili - Primera B | 2018/02/25 15:00 | La Serena v Coquimbo Unido | W | 1-0 |
| Chili - Primera B | 2018/02/18 23:00 | Nublense v La Serena | D | 1-1 |
| Chili - Primera B | 2018/02/10 23:00 | La Serena v Union San Felipe | W | 1-0 |
| Clubs internationaux - matchs amicaux | 2018/01/28 22:03 | La Serena v Deportes Vallenar | L | 0-1 |
| Clubs internationaux - matchs amicaux | 2018/01/25 22:15 | La Serena v Cobresal | W | 1-0 |