Face à face
| MLB | 2022/05/04 21:10 | SD Padres v CLE Guardians | W | 5-6 |
| MLB | 2022/05/04 17:10 | SD Padres v CLE Guardians | L | 5-4 |
| MLB - Entraînement de printemps | 2022/03/27 20:10 | CLE Guardians v SD Padres | L | 1-5 |
| MLB Exhibition | 2022/03/22 20:05 | SD Padres v CLE Guardians | W | 1-6 |
| MLB - Entraînement de printemps | 2021/03/28 20:05 | SD Padres v CLE Guardians | D | 3-3 |
| MLB - Entraînement de printemps | 2021/03/11 20:10 | CLE Guardians v SD Padres | L | 4-5 |
| MLB Exhibition | 2020/02/26 20:10 | CLE Guardians v SD Padres | L | 0-8 |
| MLB - Entraînement de printemps | 2019/03/18 20:05 | SD Padres v CLE Guardians | L | 3-1 |
Home History
| MLB | 2022/08/20 22:10 | CHI White Sox v CLE Guardians | L | 2-0 |
| MLB | 2022/08/19 23:10 | CHI White Sox v CLE Guardians | W | 2-5 |
| MLB | 2022/08/17 23:10 | DET Tigers v CLE Guardians | W | 4-8 |
| MLB | 2022/08/16 23:10 | DET Tigers v CLE Guardians | L | 4-3 |
| MLB | 2022/08/15 22:45 | DET Tigers v CLE Guardians | L | 7-5 |
| MLB | 2022/08/15 19:10 | DET Tigers v CLE Guardians | W | 1-4 |
| MLB | 2022/08/14 17:37 | CLE Guardians v TOR Blue Jays | W | 7-2 |
| MLB | 2022/08/13 19:07 | CLE Guardians v TOR Blue Jays | L | 1-2 |
Away History
| MLB | 2022/08/21 20:10 | WAS Nationals v SD Padres | W | 1-2 |
| MLB | 2022/08/21 00:40 | WAS Nationals v SD Padres | W | 1-2 |
| MLB | 2022/08/20 01:40 | WAS Nationals v SD Padres | L | 6-3 |
| MLB | 2022/08/19 01:40 | WAS Nationals v SD Padres | L | 3-1 |
| MLB | 2022/08/17 20:10 | SD Padres v MIA Marlins | W | 10-3 |
| MLB | 2022/08/16 22:40 | SD Padres v MIA Marlins | L | 3-4 |
| MLB | 2022/08/15 22:40 | SD Padres v MIA Marlins | L | 0-3 |
| MLB | 2022/08/14 16:05 | SD Padres v WAS Nationals | W | 6-0 |