Stadium: Hornet Stadium Round: 1
Home Manager: Troy Taylor Away Manager: John Stiegelmeier
| NCAAF | 2021/11/27 20:00 | UC Davis v South Dakota State | W | 24-56 |
| NCAAF | 2021/11/20 20:00 | North Dakota v South Dakota State | W | 21-24 |
| NCAAF | 2021/11/13 19:00 | South Dakota State v South Dakota | L | 20-23 |
| NCAAF | 2021/11/06 19:00 | DAKOTA DU NORD ETAT DU BISON v South Dakota State | W | 19-27 |
| NCAAF | 2021/10/30 18:00 | South Dakota State v Youngstown State | W | 47-16 |
| NCAAF | 2021/10/23 19:00 | Northern Iowa v South Dakota State | L | 26-17 |
| NCAAF | 2021/10/16 17:00 | South Dakota State v Western Illinois | W | 41-17 |
| NCAAF | 2021/10/09 19:00 | Southern Illinois v South Dakota State | L | 42-41 |
| NCAAF | 2021/11/20 21:00 | Sacramento State v UC Davis | W | 27-7 |
| NCAAF | 2021/11/14 02:00 | Portland State v Sacramento State | W | 20-49 |
| NCAAF | 2021/11/07 01:00 | Cal Poly v Sacramento State | W | 9-41 |
| NCAAF | 2021/10/30 19:00 | Sacramento State v Northern Colorado | W | 27-24 |
| NCAAF | 2021/10/24 01:00 | Northern Arizona v Sacramento State | W | 0-44 |
| NCAAF | 2021/10/16 19:00 | Sacramento State v Montana | W | 28-27 |
| NCAAF | 2021/10/10 01:00 | Southern Utah v Sacramento State | W | 20-41 |
| NCAAF | 2021/09/25 19:00 | Sacramento State v Idaho State | W | 23-21 |