Face à face
| Angleterre - Premier League 2 | 2021/03/05 14:00 | Southampton U21 v Arsenal FC Reserve | D | 2-2 |
| Angleterre - Premier League 2 | 2020/09/11 14:00 | Arsenal FC Reserve v Southampton U21 | L | 1-2 |
| Angleterre - Premier League 2 | 2019/11/23 13:00 | Arsenal FC Reserve v Southampton U21 | W | 1-0 |
| Angleterre - Premier League 2 | 2017/01/16 19:00 | Southampton U21 v Arsenal FC Reserve | W | 1-3 |
| Angleterre - Premier League 2 | 2016/10/14 18:00 | Arsenal FC Reserve v Southampton U21 | D | 0-0 |
Home History
| Angleterre - Premier League 2 | 2021/08/27 11:00 | Tottenham v Arsenal FC Reserve | W | 1-2 |
| Angleterre - Premier League 2 | 2021/08/20 18:00 | Arsenal FC Reserve v Crystal Palace | W | 4-2 |
| Angleterre - Premier League 2 | 2021/08/16 18:00 | West Ham United v Arsenal FC Reserve | L | 6-1 |
| Angleterre - Premier League 2 | 2021/05/07 18:00 | West Ham United v Arsenal FC Reserve | D | 2-2 |
| Angleterre - Premier League 2 | 2021/05/01 14:00 | Arsenal FC Reserve v West Ham United | L | 1-2 |
| Angleterre - Premier League 2 | 2021/04/26 18:00 | Leicester City U21 v Arsenal FC Reserve | D | 1-1 |
| Angleterre - Premier League 2 | 2021/04/12 18:00 | Derby County R. v Arsenal FC Reserve | W | 2-3 |
| Angleterre - Premier League 2 | 2021/03/21 13:00 | Everton v Arsenal FC Reserve | D | 1-1 |
Away History
| Angleterre - Premier League 2 | 2021/08/29 11:00 | Middlesbrough U21 v Southampton U21 | L | 2-1 |
| Angleterre - Premier League 2 | 2021/08/23 18:00 | Nottingham Forest v Southampton U21 | D | 0-0 |
| Angleterre - Premier League 2 | 2021/08/15 13:00 | Southampton U21 v Norwich City | L | 0-3 |
| Angleterre - Premier League 2 | 2021/05/07 18:00 | Everton v Southampton U21 | L | 4-0 |
| Angleterre - Premier League 2 | 2021/05/02 13:00 | Southampton U21 v Everton | L | 0-5 |
| Angleterre - Premier League 2 | 2021/04/19 18:00 | Leicester City U21 v Southampton U21 | L | 7-1 |
| Angleterre - Premier League 2 | 2021/04/12 18:00 | Chelsea U21 v Southampton U21 | L | 3-1 |
| Angleterre - Premier League 2 | 2021/04/09 13:00 | BH Albion v Southampton U21 | L | 3-0 |