Stadium: Carnie Smith Stadium Round: 1
| NCAAF | 2021/10/09 18:30 | Northwest Missouri v Pittsburg State Gorillas | L | 20-19 |
| NCAAF | 2021/10/02 19:00 | Missouri Southern Lions v Pittsburg State Gorillas | W | 16-20 |
| NCAAF | 2021/09/26 00:00 | Pittsburg State Gorillas v Emporia State | W | 30-28 |
| NCAAF | 2021/09/18 23:00 | Northeastern State Riverhawks v Pittsburg State Gorillas | W | 13-48 |
| NCAAF | 2021/09/12 00:00 | Pittsburg State Gorillas v Nebraska Kearney | L | 17-28 |
| NCAAF | 2021/09/03 00:00 | Central Missouri Mules v Pittsburg State Gorillas | W | 16-35 |
| NCAAF | 2020/11/14 22:00 | Stephen F. Austin v Pittsburg State Gorillas | L | 26-7 |
| NCAAF | 2019/11/16 19:00 | Pittsburg State Gorillas v Missouri Southern Lions | W | 65-6 |
| NCAAF | 2021/10/09 19:00 | Blue Tigers v Missouri Southern Lions | L | 32-52 |
| NCAAF | 2021/10/02 19:00 | Central Oklahoma v Blue Tigers | L | 69-28 |
| NCAAF | 2021/09/25 18:00 | Blue Tigers v Northeastern State Riverhawks | L | 48-49 |
| NCAAF | 2021/09/19 00:00 | Fort Hays State University Tigers v Blue Tigers | L | 72-0 |
| NCAAF | 2021/09/02 23:00 | Blue Tigers v Washburn Ichabods Football | L | 12-76 |
| NCAAF | 2021/02/20 00:00 | Nicholls State v Blue Tigers | L | 87-3 |
| NCAAF | 2019/11/16 18:00 | Blue Tigers v Missouri Western Griffons | L | 8-71 |
| NCAAF | 2019/11/09 19:00 | Central Missouri Mules v Blue Tigers | L | 73-6 |