Stadium: O'Kelly-Riddick Stadium Round: 1
Home Manager: Trei Oliver Away Manager: Dewayne Alexander
| NCAAF | 2021/10/02 18:30 | SE Missouri State v Tennessee Tech | W | 17-28 |
| NCAAF | 2021/09/25 18:30 | Eastern Illinois v Tennessee Tech | L | 28-14 |
| NCAAF | 2021/09/18 16:00 | Tennessee Tech v Tennessee | L | 0-56 |
| NCAAF | 2021/09/11 18:30 | Furman v Tennessee Tech | L | 26-0 |
| NCAAF | 2021/09/02 23:00 | Tennessee Tech v Samford | L | 14-52 |
| NCAAF | 2021/04/11 20:00 | Tennessee Tech v UT Martin | L | 7-40 |
| NCAAF | 2021/04/03 18:30 | Tennessee State v Tennessee Tech | W | 10-24 |
| NCAAF | 2021/03/28 19:00 | Tennessee Tech v SE Missouri State | L | 21-24 |
| NCAAF | 2021/10/02 20:00 | N.C. Central v Mississippi Valley | L | 16-17 |
| NCAAF | 2021/09/25 22:00 | N.C. Central v North Carolina A&T | L | 14-37 |
| NCAAF | 2021/09/18 22:00 | N.C. Central v Winston-Salem State | W | 20-13 |
| NCAAF | 2021/09/11 22:30 | N.C. Central v Marshall | L | 10-44 |
| NCAAF | 2021/08/28 23:00 | Alcorn State v N.C. Central | W | 14-23 |
| NCAAF | 2019/11/23 18:00 | N.C. Central v North Carolina A&T | L | 0-54 |
| NCAAF | 2019/11/16 19:00 | South Carolina State v N.C. Central | L | 24-0 |
| NCAAF | 2019/11/09 19:00 | Norfolk State v N.C. Central | L | 38-21 |